A new study conducted in Mexico employs live brain imaging of school children with and without ADHD while performing MOXO.
In this study, Juan Carlos Garcia Beristain and colleagues sought to compare differences in the brains of children with and without ADHD. They used functional magnetic resonance imaging with BOLD contrast to compare neural activation during the presentation of different visual and auditory distractors in the MOXO.
The study titled ״BOLD Activation During the Application of MOXO-CPT in School Patients With and Without Attention Deficit Hyperactivity Disorder״ was published in the Journal of Attention Disorders.
* The image has been edited to highlight MOXO test stages
Key Takeaways
- Children with ADHD show neural differences in BOLD activation compared to those without ADHD.
- Children in the control group exhibited negative BOLD inhibitory activity, especially in frontal and motor brain regions.
- Children with ADHD show overactivation of various neural regions, particularly motor areas.
* The image has been edited to highlight MOXO test stages
The study concludes that lack of inhibition, especially in frontal regions, in children with ADHD may stem from executive dysfunction, or the executive dysfunction experienced in ADHD may lead to disorganized neural activation.
You can find the abstract and link to the publication on our research & publications page.
References
García Beristain, J. C., de Celis Alonso, B., Barragan Perez, E., Dies-Suarez, P., & Hidalgo-Tobón, S. (2024). BOLD Activation During the Application of MOXO-CPT in School Patients With and Without Attention Deficit Hyperactivity Disorder. Journal of Attention Disorders, 28(3), 321-334.
